Why has polio been found in London, New York and Jerusalem, and how dangerous is it?

LONDON: Polio, a deadly disease that used to paralyse tens of thousands of children every year, is spreading in London, New York and Jerusalem for the first time in decades, spurring catch-up vaccination campaigns.

DREADED DISEASE

Polio terrified parents around the world for the first half of the 20th century. Affecting mainly children under five, it is often asymptomatic but can also cause symptoms including fever and vomiting. About one in 200 infections leads to irreversible paralysis, and among those patients, up to 10 per cent die.

There is no cure, but since a vaccine was found in the 1950s, polio is entirely preventable. Globally, the wild form of the disease has almost disappeared.

Afghanistan and Pakistan are now the only countries where the highly infectious disease, spread mainly through contact with faecal matter, remains endemic. But this year, imported cases were also found in Malawi and Mozambique, the first in those countries since the 1990s.

DIFFERENT STRAINS

There are two main forms of poliovirus. Alongside the wild-type outlined above, there are also rare cases of what is known as vaccine-derived polio.

It is this second form detected in wastewater in the British capital, London, and in New York in the United States, with one case of paralysis reported in New York state. Genetically similar virus has also been found in Jerusalem, Israel, and scientists are working to understand the link, the Global Polio Eradication Initiative (GPEI) said.

While vaccine-derived polio is almost unheard of in the above locations, it is a known – albeit rare – threat in other countries, causing outbreaks every year, including 415 cases in Nigeria in 2021.

It stems from the use of an oral polio vaccine containing weakened live virus. After children are vaccinated, they shed virus in their faeces for a few weeks. In under-vaccinated communities, this can then spread and mutate back to a harmful version of the virus.

While countries including Britain and the United States no longer use this live vaccine, others do – particularly to stop outbreaks – which allows for global spread, particularly as people began to travel again after COVID-19, experts said.