Urgent warning from health experts over deadly TikTok Benadryl challenge

Health experts have today warned about a viral but deadly TikTok trend involving one of the most popular allergy medicines.

The Benadryl Challenge has already killed two teenagers in the US. It sees people, usually kids, swallow multiple antihistamine tablets to induce hallucinations before posting videos of their experience. 

Jacob Stevens, 13, from Ohio, died on April 12 after overdosing on Benadryl as part of the social media challenge. 15-year-old Chloe Marie Phillips died in 2020.

One medic slammed the trend as a ‘death rap’, while pharmacy experts have urged social media to better monitor the ‘concerning’ challenge. 

As well as causing hallucinations, overdosing on it can result in heart failure, stroke, seizures or brain damage.

Urgent warning from health experts over deadly TikTok Benadryl challenge

Jacob Stevens took a large amount of pills as part of the Benadryl Challenge and died six days later

Jacob's family released this photo of him on life support to spread awareness of the dangers of the 'Benadryl Challenge' trend sweeping TikTok

Jacob’s family released this photo of him on life support to spread awareness of the dangers of the ‘Benadryl Challenge’ trend sweeping TikTok

On August 21, 2020, 15-year-old Chloe Marie Phillips, of Oklahoma, died after taking part in the social media challenge.

On August 21, 2020, 15-year-old Chloe Marie Phillips, of Oklahoma, died after taking part in the social media challenge.

Jacob’s body began to seize up after he downed a large amount of the allergy pills. His friends were filming to see what would happen. 

He was rushed to the hospital as his body began to shut down.

The teen was placed on a ventilator and spent six days in hospital before doctors found his brain was no longer responsive. 

Jacob’s family have begun pushing lawmakers to take steps to prevent other kids from partaking in such a challenge by putting age restrictions on over-the-counter drugs like Benadryl in the US. 

They also want to see TikTok impose an age-restriction for making accounts, forcing users to provide identification before being allowed onto the platform. 

Acrivastine — the active ingredient of Benadryl in the UK — can be bought over the counter.

Different formulations are carried across the world, with diphenhydramine used in the US.

On August 21, 2020, Chloe, of Oklahoma, died after taking part in the social media challenge.

Janette Sissy Leasure, Chloe’s great aunt, posted a now-deleted message on Facebook at the time, urging families to be on alert for kids taking part in the ‘Benadryl challenge.’

‘This needs to stop taking our kids or putting them in the hospital,’ she wrote. ‘Don’t let it take anymore kids…I don’t want to see any families go through what we are going through right now.’

Antihistamines are allergy medication that work by blocking the production of histamine — a chemical the body produces when it detects something it thinks is harmful.

In hay fever sufferers, the body mistakes pollen for a dangerous substance and releases histamine, causing symptoms such as sneezing and itchy eyes. 

Dr Leyla Hannbeck, CEO of Association of Independent Multiple Pharmacies, said: ‘It is very concerning to hear about these challenges involving medicines on social media. 

‘This is not the first time that a challenge involving over the counter medicines has led to serious harm and death.’

She urged social media to ‘take steps in monitoring this effectively’ so videos stop going viral.

And Dr Jen Caudle, a US doctor who shares videos of TikTok, said: ‘It is a death trap if you ask me and the latest tragedy is an example of this.

‘This is a warning to parents, for kids, for people out there. Do not try this.’

She added: ‘Taking too much of it can obviously cause a number of symptoms, from heart problems, to seizures, and even death – as we are seeing. 

Benadryl, also called dyphenhydromine, is a type of antihistamine. These are allergy medication that work by blocking the production of histamine - a chemical the body produces when it detects something it thinks is harmful.

Benadryl, also called dyphenhydromine, is a type of antihistamine. These are allergy medication that work by blocking the production of histamine – a chemical the body produces when it detects something it thinks is harmful. 

The 13-year-old from Ohio was remembered as a fun-loving and caring kid who could brighten anybody's day

The 13-year-old from Ohio was remembered as a fun-loving and caring kid who could brighten anybody’s day

Chloe (pictured with her father, Dustin Cook) died doing the 'Benadryl Challenge'. Her family has since warned about the dangers of the viral TikTok challenge

Chloe (pictured with her father, Dustin Cook) died doing the ‘Benadryl Challenge’. Her family has since warned about the dangers of the viral TikTok challenge

Dr Caudle said people should only take medications as described and urged parents to lock up their medications to ensure they are not easily accessible 

TikTok have taken action by banning the search for ‘Benadryl Challenge’. However, those posting videos are now using code words such as ‘bernadeyl trend’ and ‘bena tiktok challenge’, so the clips can still be found. 

Responding to the challenge in 2020, the Food and Drug administration (FDA) issued a statement warning of the dangers of participating.

‘Taking higher than recommended doses of the common over-the-counter (OTC) allergy medicine diphenhydramine (Benadryl) can lead to serious heart problems, seizures, coma or even death,’ the FDA wrote.

‘We are aware of news reports of teenagers ending up in emergency rooms or dying after participating in the ‘Benadryl Challenge’ encouraged in videos posted on the social media application TikTok.’

A spokesperson for Johnson & Johnson, the pharmaceutical giant that markets the Benadryl brand, previously said of the trend: ‘The health and safety of people who use our products is our top priority. 

‘The Benadryl TikTok trend is extremely concerning, dangerous and should be stopped immediately. 

‘As with any medicine, abuse or misuse can lead to serious side effects with potentially long-lasting consequences, and Benadryl products should only be used as directed by the label.’

What is the Benadryl challenge and why is it risky? 

What is Benadryl?

Benadryl is a type of antihistamine – allergy medication.

Antihistamines block the effects of a substance called histamine in your body. Histamine is normally released when your body detects something harmful, such as an infection.

In hay fever sufferers, the body mistakes pollen for something harmful and releases histamine to combat it. This causes allergic reaction symptoms such as sneezing and itchy eyes. 

Antihistamines, and in particular Benadryl, are known for causing drowsiness. 

What is the ‘Benadryl Challenge’? 

The ‘Benadryl Challenge’ is a viral trend that sees people take large amounts of the drug, in an attempt to hallucinate. 

The amount taken in this challenge can be considerably more than the strict dosage of no more than six tablets in 24 hours. 

Research published in the Clinical Toxicology journal found that in children, Benadryl causes increased heart rate and vivid hallucinations.

Why is the ‘Benadryl Challenge’ dangerous? 

Experts say that while Benadryl can cause hallucinations, it can also induce many other serious serious effects.

Dr Kenneth Perry, of US-based Trident Medical Center, says when taken in excess, antihistamines can cause ‘severe overheating and potential cardiovascular failure’, as well as seizures.

He says this can occur as a result of a rocketing heart rate and elevated blood pressure.

The most common side effects of an overdose include irregular heart beats, decreased urinary retention, vision changes and flushed skin.

The doses taken are also extremely high. 

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