SARSCoV2

Immune T cells are continuing to target the spike protein of SARS-CoV-2 variants of concern, although mutations are making some T cells less effective, according to new research. Published in Nature Immunology, researchers from the…

mRNA COVID-19 vaccines are less effective against Omicron infections than other variants. A study publishing December 1 in the open access journal PLOS Medicine by Margaret L. Lind at the Yale School of Public Health, U.S. and colleagues…

First discovered a year ago in South Africa, the SARS-CoV-2 variant later dubbed "Omicron" spread across the globe at incredible speed. It is still unclear exactly how, when and where this virus originated. Now, a study published in the…

An analysis of massive amounts of genetic data on the SARS-CoV-2 virus suggests that COVID-19 variants worldwide are repeatedly evolving the same mutations, according to a study published today in eLife and carried out by researchers at the…

Researchers at the University of Maryland School of Medicine's (UMSOM) Center for Precision Disease Modeling identified how a specific protein in SARS-CoV-2, the virus responsible for COVID-19, damages heart tissue. They then used a drug to…

Using human brain organoids, an international team of researchers, led by scientists at University of California San Diego School of Medicine and Sanford Consortium, has shown how the SARS-CoV-2 virus that causes COVID-19 infects cortical…

The total magnitude of the T-cell responses induced by mRNA and inactivated SARS-CoV-2 vaccines are comparable; however, the similarity ends here, according to a new study led by Duke-NUS Medical School scientists. They found that the…

In a recent study that represents the largest to date to examine the severity of the SARS-CoV-2 Omicron BA.2 subvariant (the strain making a re-emergence this fall), a team led by investigators at Massachusetts General Hospital (MGH)…

Dysregulation of macrophages during SARS-CoV-2 infection and the over-exuberant production of pro-inflammatory cytokines by these macrophages has been hypothesized to contribute to severity of COVID-19 disease. However, the mechanisms that…

What exactly are the molecular interactions between the virus causing COVID-19 and its human host? How might our genetic differences cause different disease courses? And how do still-emerging virus variants differ in their host-virus…