macrophages

Current treatments for atrial fibrillation (AFib), a common heart condition characterized by fast and irregular beats that can lead to stroke and heart failure, have multiple side effects and are ineffective for preventing AFib recurrence.…

When our bodies become infected, various immune responses are triggered, starting with a release of granulocytes, white blood cells containing special enzymes that make up about half or more of all human white blood cells. Neutrophils are…

The human immune system is a highly complex network of cells, signals, and responses that is tightly regulated to ensure that the body can fight off infection without damaging its own tissues. Now, researchers from Japan report a new way in…

Dysregulation of macrophages during SARS-CoV-2 infection and the over-exuberant production of pro-inflammatory cytokines by these macrophages has been hypothesized to contribute to severity of COVID-19 disease. However, the mechanisms that…

In one of the largest single-center COVID-19 cohort studies to date, researchers at the Icahn School of Medicine at Mount Sinai, using samples collected during the peak of the pandemic in New York City, have identified a key driver of…

New discovery on the causes of PAP lung disease can also offer solutions for treating obesity and heart disease. The research group has identified a genetic defect that causes the accumulation of lipids in the pulmonary alveoli.Pulmonary…

Macrophages are key cells of our innate immune response. By populating almost all tissues in our body, these cells have an essential role in maintaining our organs in a healthy state, as they constantly remove dying cells or eliminate…

Patients with heart disease are at risk of experiencing a potentially lethal "electrical storm" involving recurrent episodes of a type of irregular heartbeat called ventricular tachycardia (VT). Electric shock therapy is used to treat VT…

Metastatic breast cancer cells abuse macrophages, a type of immune cell, to promote the settlement of cancer metastases in the lungs. The reprogrammed macrophages stimulate blood vessel cells to secrete a cocktail of metastasis-promoting…

Cancer researchers at the Case Western Reserve University School of Medicine say they have successfully suppressed the growth of some solid tumors in research models by manipulating immune cells known as a macrophages. The researchers say…