inhibitor

When the COVID-19 pandemic hit, scientists across the U.S. Department of Energy's (DOE) national laboratory complex turned to the nation's most powerful supercomputers and other tools to discover molecules that might treat the disease. A…

A protein known as Lefty pumps the brakes as human embryos begin to differentiate into the bones, soft tissues and organs that make us. This inhibitor protein is key during the early stages of life when the fates of embryonic stem cells are…

Researchers at Penn Medicine have discovered a new, more effective method of preventing the body's own proteins from treating nanomedicines like foreign invaders, by covering the nanoparticles with a coating to suppress the immune response…

Combining a histone deacetylase inhibitor drug with immunotherapy agents is safe, and may benefit some patients with advanced cancers that have not responded to traditional therapy, according to results of a phase 1 clinical trial led by…

Remetinostat, a topical cream and first-in-class inhibitor of histone deacetylation, showed signs of clinical efficacy in patients with basal cell carcinoma. Basal cell carcinoma (BCC) is the most common form of skin cancer and is typically…