Genomic

A new statistical method provides a more efficient way to uncover biologically meaningful changes in genomic data that span multiple conditions -- such as cell types or tissues. Whole genome studies produce enormous amounts of data, ranging…

A research team led by a University of Massachusetts Amherst scientist has made a significant genetic discovery that sheds light on the use of the drug caspofungin to treat a deadly fungal infection, Aspergillus fumigatus, which kills some…

New research -- which studied genomic changes in different types of brain cell -- has yielded a potentially surprising result: many of the changes in Alzheimer's disease are in brain cells other than neurons, the cells that actually die as…

Scientists have created a roadmap of the genetic mutations present in the most common childhood cancer, acute lymphoblastic leukemia (ALL). The St. Jude Children's Research Hospital study is the first to supply a comprehensive view of the…

An analysis of millions of SARS-CoV-2 genomes finds that recombination of the virus is uncommon, but when it occurs, it is most often in the spike protein region, the area which allows the virus to attach to and infect host cells. The…

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Scientists today can access genomic data from Indigenous Peoples without their free, prior, and informed consent, leading to potential misuse and the reinforcement of stereotypes. Despite existing tools that facilitate the sharing…

Malaria is the deadliest mosquito-borne parasitic infection of humans. In 2021, after a century of research, the World Health Organization (WHO) approved the world's first malaria vaccine. That vaccine reduces the incidence of malaria…

Microbes taken from surface sediment near Lost Hammer Spring, Canada, about 900 km south of the North Pole, could provide a blueprint for the kind of life forms that may once have existed, or may still exist, on Mars. The extremely salty,…

Though underlying medical conditions play an important role, many aspects of why COVID-19 severity can differ vastly from one to another has remained unclear. A new study identifies dozens of genomic variations that may drive these…