Genomic

Watermelon is a globally significant agricultural product, both in terms of the total amount produced and the total economic value generated. Scientists at the Boyce Thompson Institute have constructed a comprehensive "super-pangenome" for…

Researchers have uncovered two new cholera substrains in a displaced refugee population in southern Bangladesh, where a pre-emptive mass vaccination campaign of over one million refugees was successful in preventing an epidemic. They also…

Polygenic scores -- estimates of an individual's predisposition for complex traits and diseases -- hold promise for identifying patients at risk of disease and guiding early, personalized treatments, but UCLA experts found the scores fail…

For more than 20 years, scientists have relied on the human reference genome, a consensus genetic sequence, as a standard against which to compare other genetic data. Used in countless studies, the reference genome has made it possible to…

UC Santa Cruz scientists, along with a consortium of researchers, have released a draft of the first human pangenome -- a new, usable reference for genomics that combines the genetic material of 47 individuals from different ancestral…

Africa, where humans first evolved, today remains a place of remarkable diversity. Diving into that variation, a new analysis of 180 indigenous Africans from a dozen ethnically, culturally, geographically, and linguistically varied…

A genomic study of a sustained, multidrug-resistant Shigellosis outbreak in Seattle enabled scientists to retrace its origin and spread. Additional analysis of the gut pathogen and its transmission patterns helped direct approaches to…

LONDON: Genomic sequencing allowed the world to track new coronavirus variants throughout the pandemic. Now British researchers plan to use it to better understand a host of other respiratory pathogens, from influenza to respiratory…

National Institutes of Health researchers have published an assessment of 13 studies that took a genotype-first approach to patient care. This approach contrasts with the typical phenotype-first approach to clinical research, which starts…

The gene DDX41 encodes the nuclear enzyme, DEAD-box-type RNA helicase. Mutation of DDX41 leads to hematopoietic cancers. However, the mechanism underlying this malignancy development is unclear. To this end, researchers from Japan…