bloodbrain

What makes the vital layer of protective cells around the brain and spinal cord -- the blood-brain barrier -- more or less permeable has been one of the more mystifying questions in neuroscience. Understanding how the barrier works to allow…

A new, biodegradable ultrasound far more powerful than previous devices could make brain cancers more treatable, University of Connecticut researchers report in the June 14 issue of Science Advances. Brain cancer affects more than 24,000…

There's a bouncer in everyone: The blood-brain barrier, a layer of cells between blood vessels and the rest of the brain, kicks out toxins, pathogens and other undesirables that can sabotage the brain's precious gray matter. When the…

A major impediment to treating the deadly brain cancer glioblastoma has been that the most potent chemotherapy can't permeate the blood-brain barrier to reach the aggressive brain tumor. But now Northwestern Medicine scientists report…

Sometimes the best things in life come by chance, when we happen to be in the right place at the right time. Now, researchers from Japan have found a way to ensure that new medications are delivered to the right place in the body and at the…

Mario Modena is a postdoc working in the Bio Engineering Laboratory at ETH Zurich. If he were to explain his research on the blood-brain barrier -- the wall that protects our central nervous system from harmful substances in the blood…

The blood-brain barrier (BBB) is an imposing foe for gene therapy. Formed of cells wedged tightly together, the BBB keeps toxins and pathogens that may be present in the blood from entering brain tissue, but it also keeps out potential…

While the role of the blood-brain barrier has long been appreciated for its ability to maintain precise control over what molecules can enter the nervous system, very little is known about how the cells that form the barrier influence the…

The brain is composed of billions of neurons -- vulnerable cells that require a protective environment to function properly. This delicate environment is protected by 400 miles of specialized vasculature designed to limit which substances…

The blood-brain barrier plays an essential role in protecting the central nervous system from harmful bacteria, toxins, and other blood-borne pathogens. Composed of a tight row of endothelial cells, the barrier is semipermeable and highly…