antimalarial

A large-scale study by the Swiss Tropical and Public Health Institute (Swiss TPH) and partners has found that rectal artesunate (RAS) has no beneficial effect on the survival of young children with severe malaria when used as an emergency…

A new antimalarial drug is being introduced at a dose that is too low to be effective for all patients who need it, according to a report published today in eLife. The study suggests that the current 300 mg adult dose of tafenoquine reduces…

Sub-Saharan Africa accounts for a disproportionately high share of the global malaria burden, with around 96 per cent of all cases and deaths in 2020.    As a result of drug resistance, medicines to treat the life-threatening disease…

The function of an enzyme, critical to most forms of life, has been revealed. A research team, led by the John Innes Centre found that the enzyme DNA topoisomerase VI (topo VI) performs a critical role in removing chromosome tangles that…

A study out of the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University has resulted in the discovery of a promising new antimalarial compound. Co-led by Gerry Wright, professor of biochemistry &…

Altering a mosquito's gut genes to make them spread antimalarial genes to the next generation of their species shows promise as an approach to curb malaria, suggests a preliminary study published today in eLife. The study is the latest in a…