anticancer

Scientists at St. Jude Children's Research Hospital found immune and tumor cells compete over glutamine, a major nutrient in their local environment, with significant implications for anti-cancer activity. If cancer cells monopolize…

Chemotherapy treatments produce strong side effects. A new agent that accumulates in the tumour tissue and is activated there by ultrasound waves does not have this problem. Platinum complexes are among the most commonly used drugs against…

Fibroblasts build and maintain the extracellular matrix, or physical scaffolding for cells, in the connective tissues within the body. It is believed that cancerous tumors can recruit nearby fibroblasts and use them to promote their own…

New research from the Centre for Cancer Immunology at the University of Southampton, published ahead of World Cancer Day (4 February), has shown that changing how tightly an antibody binds to a target could improve treatments for cancer.…

The evolutionary secrets that enable the medicinal herb known as barbed skullcap to produce cancer fighting compounds have been unlocked by a collaboration of UK and Chinese researchers. The CEPAMS collaboration used DNA sequencing…

A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers. The drug stalled the growth of tumors in the five people in the trial with…

Scientists from Oxford University and the University of Birmingham have made the first bone marrow 'organoids' that capture the key features of human bone marrow. This technology, which is the subject of a patent application filed by…

Researchers from the Epigenetics and Immune Disease Lab at the Josep Carreras Leukaemia Research Institute have recently shown that vitamin C improves the immunogenic properties of dendritic cells, in vitro. Results recently made public…

Based on findings from a new study by a Johns Hopkins Medicine-led research team, an effective means of fighting SARS-CoV-2, the virus that causes COVID-19, may be possible that circumvents the problem of waning immunity often observed when…

A study led by LSU Health New Orleans cancer researchers describes a novel therapeutic strategy to overcome tumor-induced immunosuppression. For the first time, the research team identified a critical immunosuppressive pathway and a…