Spurs turned up the pressure with James Maddison going close with a long-range effort which forced a fine diving save from Sailors goalkeeper Zharfan Rohaizad.
Son Heung-min headed home after 26 minutes but his effort was ruled out for offside while Pape Matar Sarr skimmed the crossbar with a volley.
However, Tottenham’s pressure finally told in first-half stoppage time when Sarr was brought down in the Sailors box and Kane stepped up to send Zharfan the wrong way from the penalty spot to level things up.
Postecoglou made 11 changes at half-time and his new line-up took the lead just three minutes after the restart.
Lo Celso’s effort deflected off a defender and the ball fell nicely for Richarlison to turn the ball into the net.
The Brazilian was again on target five minutes later when he pounced on a weak back-header to nod in his second of the game.
While the Tottenham striker was twice denied a hat-trick goal by the offside flag, his side managed to add a fourth goal in the 73rd minute when Lo Celso drove home a loose ball in the six-yard box.
And Richarlison’s persistence was finally rewarded in stoppage time when he burst through the centre of the Sailors defence and flicked in his third goal of the game to make it 5-1.
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